RETRACTED ARTICLE: CHEMICAL INHIBITION REVEALS DIFFERENTIAL REQUIREMENTS OF SIGNALING PATHWAYS IN KRASV12- AND MYC-INDUCED LIVER TUMORS IN TRANSGENIC ZEBRAFISH

Abstract Previously we have generated inducible liver tumor models by transgenic expression of an oncogene and robust tumorigenesis can be rapidly induced by activation of the oncogene in both juvenile and adult fish.In the present study, we aimed at chemical intervention of tumorigenesis for understanding molecular pathways of tumorigenesis and fo

Salmonella enterica serovar Typhimurium is a common food-borne pathogen that induces inflammatory diarrhea and invades intestinal epithelial cells using a type three secretion system (T3SS) encoded within Salmonella pathogenicity island 1 (SPI1).The genes encoding the SPI1 T3SS are tightly regulated by a network of interacting transcriptional regul

To further improve the performance of the Proton Exchange Membrane Fuel Cell (PEMFC), in this paper, we designed a blocked flow channel with trapezoidal baffles, and geometric parameters of the baffle were optimized based on CFD simulation, Artificial Neural Network (ANN), and single-objective optimization methods.The analysis of velocity, pressure